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What (who) is N-terminal - definition
N-Terminal domain antiandrogen
DRUG CLASS
Peptide antiandrogens; Peptide antiandrogen; N-terminal domain antiandrogen; N-terminal domain androgen receptor antagonist; N-Terminal domain androgen receptor antagonist
N-Terminal domain antiandrogens are a novel type of antiandrogen that bind to the N-terminal domain of the androgen receptor (AR) instead of the ligand-binding domain (where all currently-available antiandrogens bind) and disrupt interactions between the AR and its coregulatory binding partners, thereby blocking AR-mediated gene transcription. They are being investigated for the treatment of prostate cancer.
N-Terminal peptide of proopiomelanocortin
PROTEIN IN HOMO SAPIENS
N-terminal peptide of proopiomelanocortin; N-terminal peptide of pro-opiomelanocortin; N-Terminal peptide of pro-opiomelanocortin; N-Terminal peptide of POMC; N-terminal peptide of POMC; N-terminal fragment of POMC; N-Terminal fragment of POMC; N-Terminal fragment of proopiomelanocortin; N-terminal fragment of proopiomelanocortin; N-terminal fragment of pro-opiomelanocortin; N-Terminal fragment of pro-opiomelanocortin; N-POMC; Pro-γ-MSH; Pro-gamma-MSH; Pro-Gamma-MSH
The N-terminal peptide/fragment of proopiomelanocortin (NPP; N-POMC), also known as pro-γ-MSH, is a naturally occurring, endogenous metabolite of the polypeptide proopiomelanocortin (POMC).
YgbB N terminal protein domain
In molecular biology, YgbB is a protein domain. This entry makes reference to a number of proteins from eukaryotes and prokaryotes which share this common N-terminal signature and appear to be involved in terpenoid biosynthesis.
